The Bed ubiquitin-proteasome system plays important roles in various biological processes as it degrades the majority of cellular proteins.Adequate proteasomal degradation of crucial transcription regulators ensures the proper development of neutrophils.The ubiquitin E3 ligase of Growth factor independent 1 (GFI1), a key transcription repressor gov
The Flavivirus genus contains important pathogens, such as West Nile virus (WNV), Zika virus (ZIKV), and Dengue virus (DENV), which are enveloped plus-strand RNA viruses transmitted by mosquitoes and constitute a worrisome threat to global human and animal health.Currently no licensed drugs against them are available, being, thus, still necessary t
Abstract Paragangliomas arise from paraganglion cells which serve varied regulatory tasks Gift Card in the body.When these cells demonstrate neoplasia within the head and neck, they typically present in characteristic locations including the carotid space, the jugular foramen, the middle ear, and along the course of the vagus nerve.The goal of this